Holzman RS., Clinical management of latex-allergic children.Clinical management of latex-allergic children. Anesthesia & Analgesia. 1997;85(3):529-33.
Latex allergy in children with myelodysplasia and urological anomalies is well recognized. The authors anesthetized 162 children with latex allergy who underwent 267 anesthetics according to a latex-safe protocol. Medication for allergy prophylaxis was not administered. The patients were 11.6 +/- 5.8 yr old (range 1-31 yr). Primary diagnoses were myelodysplasia, extrophy of the bladder, and cloacal extrophy. The children had many allergies to medications and foods as well as environmental sensitivities. One patient of 162 (one procedure of 267) had an allergic reaction after injection of an epidural catheter with bupivacaine and fentanyl. No other patient manifested allergy signs or symptoms. The authors suggest that latex-allergic children can be safely anesthetized using a latex-safe protocol without allergy chemoprophylaxis. These patients require avoidance of latex products or the use of latex products that have been thoroughly washed.